Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.85 |
| ▸ | MMP12 | P39900 | 15/20 | 0.85 |
| ▸ | MMP9 | P14780 | 14/20 | 0.85 |
| ▸ | MMP13 | P45452 | 13/20 | 0.85 |
| ▸ | MMP14 | P50281 | 13/20 | 0.85 |
| ▸ | MMP8 | P22894 | 10/20 | 0.85 |
| ▸ | MMP16 | P51512 | 10/20 | 0.85 |
| ▸ | MMP3 | P08254 | 11/20 | 0.71 |
| ▸ | MMP1 | P03956 | 9/20 | 0.71 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228783 | 0.92 | MMP2 (1.00) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL5898999 | 0.86 | MMP2 (0.84) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL8365097 | 0.86 | MMP2 (0.73) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL8228874 | 0.83 | MMP2 (1.00) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL13401706 | 0.82 | MMP2 (0.75) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL10049367 | 0.77 | MMP2 (0.73) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL4434930 | 0.76 | MMP8 (0.60) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL316301 | 0.76 | MMP2 (0.87) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL146566 | 0.75 | HTT (0.81) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL17559302 | 0.75 | HTT (0.81) | MMP2MMP12MMP9MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |