Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.71 |
| ▸ | MMP9 | P14780 | 6/20 | 0.71 |
| ▸ | MMP12 | P39900 | 6/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MMP14 | P50281 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP16 | P51512 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316248 | 0.92 | MMP2 (0.85) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL9152799 | 0.88 | CYP2C9 (0.57) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL315440 | 0.87 | MMP2 (0.92) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL3765157 | 0.85 | HPGD (0.78) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL5905654 | 0.83 | MMP2 (0.64) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL315140 | 0.83 | MMP2 (1.00) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL6933325 | 0.83 | CYP2C9 (0.74) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL8228112 | 0.83 | MMP2 (0.76) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL8229735 | 0.81 | CYP2C9 (0.72) | MMP2MMP9MMP12CYP2C9CYP2C19 | |
| SCHEMBL4734978 | 0.81 | CYP2C9 (0.72) | MMP2MMP9MMP12CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |