Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 3/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12210573 | 0.77 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1CCR2MMP1 | |
| SCHEMBL10160076 | 0.77 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1CCR2MMP1 | |
| SCHEMBL6734281 | 0.77 | L3MBTL1 (0.43) | L3MBTL1KDM4EALDH1A1CCR2MMP1 | |
| SCHEMBL12875886 | 0.72 | CCR2 (0.41) | L3MBTL1KDM4EALDH1A1CCR2MMP1 | |
| SCHEMBL3397946 | 0.72 | CCR2 (0.41) | L3MBTL1KDM4EALDH1A1CCR2MMP1 | |
| SCHEMBL6732580 | 0.71 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1CCR2POLB | |
| SCHEMBL28358586 | 0.70 | HTT (0.39) | L3MBTL1KDM4EALDH1A1CCR2MMP1 | |
| SCHEMBL23835858 | 0.69 | CCR2 (0.43) | L3MBTL1KDM4EALDH1A1CCR2 | |
| SCHEMBL24019640 | 0.68 | CCR2 (0.39) | L3MBTL1KDM4EALDH1A1CCR2 | |
| SCHEMBL6079957 | 0.67 | SLC6A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |