Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.59 |
| ▸ | MMP2 | P08253 | 6/20 | 0.57 |
| ▸ | MMP8 | P22894 | 6/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | CCKAR | P32238 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14177510 | 0.93 | CCKBR (0.61) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8236296 | 0.92 | MMP2 (0.59) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8426512 | 0.92 | MMP2 (0.63) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL24122290 | 0.90 | ECE1 (0.60) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8360548 | 0.90 | CCKBR (0.65) | CCKBRCCKAR | |
| SCHEMBL8363652 | 0.88 | CCKBR (0.61) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8235648 | 0.88 | MMP2 (0.62) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8245264 | 0.87 | MMP2 (0.58) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8242675 | 0.87 | MMP2 (0.58) | CCKBRMMP2MMP8MMP1MMP9 | |
| SCHEMBL8363817 | 0.87 | MMP2 (0.62) | CCKBRMMP2MMP8MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |