Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364318 | 1.00 | MME (0.39) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL22414041 | 0.79 | CA2 (0.47) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL9359890 | 0.78 | ALDH1A1 (0.45) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL444915 | 0.77 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL194100 | 0.77 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL194101 | 0.77 | MME (0.41) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL9500789 | 0.75 | — | — | |
| SCHEMBL9500795 | 0.75 | — | — | |
| SCHEMBL3507245 | 0.73 | TGFBR1 (0.55) | MMERAB9AACECPA1ACE2 | |
| SCHEMBL12694106 | 0.73 | TGFBR1 (0.55) | MMERAB9AACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804735-A4 | N-TERMINAL PROTEIN SEQUENCING REAGENTS AND METHODS WHICH FORM AMINO ACID DERIVATIVES | HOPE CITY (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5807748-A | N-terminal protein sequencing reagents and methods which form amino acid detectable by a variety of techniques | CITY OF HOPE (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0804735-A1 | N-TERMINAL PROTEIN SEQUENCING REAGENTS AND METHODS WHICH FORM AMINO ACID DERIVATIVES | CITY OF HOPE (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996002003-A1 | N-TERMINAL PROTEIN SEQUENCING REAGENTS AND METHODS WHICH FORM AMINO ACID DERIVATIVES | CITY OF HOPE (US) | 1996-01-25 | — | — | WO | disclosed |