SCHEMBL8364617

SCHEMBL8364617

C=CC(=O)OC(C(=O)O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
SRC P12931 1/20 0.42
THRB P10828 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
LMNA P02545 2/20 0.41
MAPK1 P28482 1/20 0.41
AKT1 P31749 1/20 0.39
PPARA Q07869 3/20 0.39
PPARG P37231 1/20 0.39
KDM4E B2RXH2 1/20 0.37
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991997 0.86 ALDH1A1 (0.40) CYP2C19ALDH1A1CYP3A4CYP2D6SRC
SCHEMBL28110630 0.86 ALDH1A1 (0.47) CYP2C19ALDH1A1CYP3A4CYP2D6SRC
SCHEMBL37125 0.84 ALDH1A1 (0.63) CYP2C19ALDH1A1CYP3A4LMNAAKT1
SCHEMBL11062249 0.84 ALDH1A1 (0.46) CYP2C19ALDH1A1CYP3A4THRBHCAR2
SCHEMBL18269392 0.83 KMT2A (0.51) ALDH1A1CYP3A4THRBHCAR2LMNA
Water SCHEMBL5357502 0.83 ALDH1A1 (0.61) CYP2C19ALDH1A1CYP3A4LMNAAKT1
SCHEMBL24708816 0.81 THRB (0.43) CYP2C19ALDH1A1CYP3A4CYP2D6SRC
SCHEMBL30881617 0.81 THRB (0.43) CYP2C19ALDH1A1CYP3A4CYP2D6SRC
SCHEMBL439256 0.81 ESR1 (0.49) CYP2C19ALDH1A1CYP2D6SRCTHRB
SCHEMBL18269390 0.80 MMP8 (0.47) ALDH1A1THRBLMNAKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078379-B2 Method for the prevention of mist formation in a device comprising rolls during the coating of flexible media with a crosslinkable liquid silicone composition ELKEM SILICONES FRANCE SAS (FR) 2021-08-03 US claimed
CN-109952352-B Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus 埃肯有机硅法国简易股份公司 2021-04-20 CN claimed
CN-107429063-B Organopolysiloxane and method for producing the same 埃肯有机硅法国简易股份公司 2021-03-23 CN claimed
EP-3472252-B1 METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION ELKEM SILICONES FRANCE S A S (FR) 2020-04-01 EP claimed
US-20190249036-A1 METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION INSTITUT NATIONAL DES SCIENCES APPLIQUÉES (FR) 2019-08-15 US claimed
US-10358541-B2 Organopolysiloxanes and methods for preparing same ELKEM SILICONES FRANCE SAS (FR) 2019-07-23 US claimed
EP-3472252-A1 METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION Elkem Silicones France S.A.S. (FR) 2019-04-24 EP claimed
US-20180265668-A1 ORGANOPOLYSILOXANES AND METHODS FOR PREPARING SAME ELKEM SILICONES FRANCE SAS (FR) 2018-09-20 US claimed
US-5871894-A CONTAINING CYAN DYE-FORMING COUPLER AND ADDITION COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1999-02-16 US claimed
EP-0881535-A1 Silver halide color photographic light-sensitive material Fuji Photo Film Co., Ltd. (JP) 1998-12-02 EP claimed
US-20220106471-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2022-04-07 US disclosed
US-11078379-B2 Method for the prevention of mist formation in a device comprising rolls during the coating of flexible media with a crosslinkable liquid silicone composition ELKEM SILICONES FRANCE SAS (FR) 2021-08-03 US disclosed
CN-109952352-B Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus 埃肯有机硅法国简易股份公司 2021-04-20 CN disclosed
CN-107429063-B Organopolysiloxane and method for producing the same 埃肯有机硅法国简易股份公司 2021-03-23 CN disclosed
WO-2020158688-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER 日本ポリエチレン株式会社 2020-08-06 WO disclosed
CN-109952352-A Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus 埃肯有机硅法国简易股份公司 2019-06-28 CN disclosed
US-20180265668-A1 ORGANOPOLYSILOXANES AND METHODS FOR PREPARING SAME ELKEM SILICONES FRANCE SAS (FR) 2018-09-20 US disclosed
CN-105102569-B Sticker and its application 东洋油墨SC控股株式会社 2018-04-03 CN disclosed
CN-107429063-A Organopolysiloxane and method for producing the same 蓝星有机硅法国两合公司 2017-12-01 CN disclosed
US-9255104-B2 Cyclopropyl modulators of P2Y12 receptor AUSPEX PHARMACEUTICALS, INC. (US) 2016-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10358541-B2 Organopolysiloxanes and methods for preparing same IDUA, MAN2B1, ALG1 CYP2C19 2086/4885ALDH1A1 267/4885CYP3A4 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.