Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthylamine SCHEMBL8515807 | 0.89 | PTPN1 (0.47) | PTPN1CTSSCTSKCTSBGABRB1 | |
| SCHEMBL1982893 | 0.83 | ITGB3 (0.50) | PTPN1CTSSCTSKCTSBACE | |
| SCHEMBL1982889 | 0.83 | ITGB3 (0.50) | PTPN1CTSSCTSKCTSBACE | |
| SCHEMBL1980173 | 0.75 | PPARA (0.48) | CTSSCTSKCTSBACEPPARA | |
| SCHEMBL1980172 | 0.75 | PPARA (0.48) | CTSSCTSKCTSBACEPPARA | |
| SCHEMBL8174447 | 0.74 | ACE (0.57) | PTPN1CTSSCTSKCTSBACE | |
| SCHEMBL7857062 | 0.74 | ACE (0.57) | PTPN1CTSSCTSKCTSBACE | |
| SCHEMBL2398131 | 0.74 | CTSK (0.44) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL1519731 | 0.74 | CTSS (0.74) | PTPN1CTSSCTSKCTSBACE | |
| SCHEMBL3821361 | 0.74 | CTSS (0.74) | PTPN1CTSSCTSKCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |