Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347758 | 0.99 | SIRT2 (0.55) | SIRT2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL13617948 | 0.83 | SIRT2 (0.47) | SIRT2ALDH1A1LMNA | |
| SCHEMBL22356512 | 0.81 | SIRT2 (0.61) | SIRT2ALDH1A1NMBR | |
| SCHEMBL2000374 | 0.81 | SIRT2 (0.61) | SIRT2ALDH1A1NMBR | |
| SCHEMBL1999739 | 0.80 | SIRT2 (0.60) | SIRT2NMBR | |
| SCHEMBL10026712 | 0.80 | SIRT2 (0.60) | SIRT2NMBR | |
| SCHEMBL523065 | 0.80 | SIRT2 (0.60) | SIRT2NMBR | |
| SCHEMBL522051 | 0.80 | SIRT2 (0.60) | SIRT2NMBR | |
| SCHEMBL8348613 | 0.80 | SIRT2 (0.46) | SIRT2 | |
| SCHEMBL8366352 | 0.80 | SIRT2 (0.46) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003061653-A1 | 3-(IMIDAZOLYL)-2-AMINOPROPANOIC ACIDS FOR USE AS TAFI-A INHIBITORS FOR THE TREATMENT OF THROMBOTIC DISEASES | PFIZER LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |