Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455582 | 0.84 | MC4R (0.56) | — | |
| SCHEMBL13437223 | 0.83 | EPHX1 (0.47) | RAB9ASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8362464 | 0.83 | LTA4H (0.56) | RAB9ASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL9489894 | 0.82 | MEN1 (0.49) | RAB9ASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL7618233 | 0.79 | LTA4H (0.61) | RAB9ASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8591091 | 0.79 | RAB9A (0.50) | RAB9ASMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL7860801 | 0.77 | LTA4H (0.51) | SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL7850353 | 0.76 | LTA4H (0.50) | MEN1KMT2ALMNAROCK2HTR1E | |
| SCHEMBL7857988 | 0.76 | FCER2 (0.46) | RAB9ANPC1 | |
| SCHEMBL9195141 | 0.76 | RAB9A (0.50) | RAB9ASMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |