SCHEMBL7618233

SCHEMBL7618233

NCCCC[C@H](N)C(=O)Nc1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 1/20 0.61
▸ TERT O14746 3/20 0.52
▸ DPP8 Q6V1X1 1/20 0.49
▸ DPP9 Q86TI2 1/20 0.49
▸ DPP7 Q9UHL4 1/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ MAPT P10636 2/20 0.49
▸ POLB P06746 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ MMP2 P08253 2/20 0.48
▸ RAB9A P51151 4/20 0.48
▸ SMN1; SMN2 Q16637 3/20 0.48
▸ GAA P10253 1/20 0.48
▸ ROCK2 O75116 2/20 0.47
▸ CYP1A2 P05177 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ HIF1A Q16665 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8362464 0.96 LTA4H (0.56) LTA4HTERTDPP8DPP9DPP7
SCHEMBL9195141 0.86 RAB9A (0.50) LTA4HTERTDPP8DPP9DPP7
SCHEMBL9195147 0.86 RAB9A (0.50) LTA4HTERTDPP8DPP9DPP7
SCHEMBL7859203 0.85 LTA4H (0.55) LTA4HMMP2SMN1; SMN2
SCHEMBL4607283 0.85 MEN1 (0.48) LTA4HDPP8DPP9DPP7MEN1
SCHEMBL7850346 0.84 LTA4H (0.54) LTA4HTERTMMP2ROCK2
SCHEMBL13820164 0.83 LTA4H (0.70) LTA4HTERTDPP8DPP9DPP7
SCHEMBL21753952 0.82 MEN1 (0.50) LTA4HMEN1KMT2AMAPTPOLB
SCHEMBL29395053 0.82 LTA4H (0.62) LTA4HMEN1KMT2AMAPTPOLB
SCHEMBL166772 0.82 MEN1 (0.50) LTA4HMEN1KMT2AMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0633316-A1 Lys-aminopeptidase PepN from lactobacillus delbruckii ssp. Lactis, nucleic acids coding for it, and its use in fermentation processes EUROPEAN ECONOMIC COMMUNITY E.E.C. (LU) 1995-01-11 — — EP claimed
US-4603108-A Method for identification of bacterial species NATIONAL RESEARCH DEVELOPMENT CORP. (GB) 1986-07-29 — — US claimed
EP-0018825-B1 A PROCESS FOR THE IDENTIFICATION OF BACTERIA AND A KIT OF REAGENTS FOR USE IN THIS PROCESS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-02-13 — — EP claimed
US-20020198254-A1 Polyamide analogs GENELABS TECHNOLOGIES, INC. 2002-12-26 — — US disclosed
WO-2002062755-A2 POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS GENELABS TECHNOLOGIES, INC. (US) 2002-08-15 — — WO disclosed
EP-0633316-A1 Lys-aminopeptidase PepN from lactobacillus delbruckii ssp. Lactis, nucleic acids coding for it, and its use in fermentation processes EUROPEAN ECONOMIC COMMUNITY E.E.C. (LU) 1995-01-11 — — EP disclosed
EP-0313997-B1 Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds HOECHST AG (DE) 1994-03-09 — — EP disclosed
EP-0255341-B1 REAGENT FOR TESTING PERIODONTAL DISEASES SUNSTAR KABUSHIKI KAISHA (JP) 1993-02-03 — — EP disclosed
US-5137811-A Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria SUNSTAR KABUSHIKI KAISHA (JP) 1992-08-11 — — US disclosed
US-5006515-A Immunology disorders, antitumor agent HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-09 — — US disclosed
EP-0313997-A2 Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-03 — — EP disclosed
EP-0255341-A2 Reagent for testing periodontal diseases SUNSTAR KABUSHIKI KAISHA (JP) 1988-02-03 — — EP disclosed
US-4603108-A Method for identification of bacterial species NATIONAL RESEARCH DEVELOPMENT CORP. (GB) 1986-07-29 — — US disclosed
EP-0018825-B1 A PROCESS FOR THE IDENTIFICATION OF BACTERIA AND A KIT OF REAGENTS FOR USE IN THIS PROCESS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-02-13 — — EP disclosed
WO-1980002433-A1 THE IDENTIFICATION OF BACTERIA NAT RES DEV (GB) 1980-11-13 — — WO disclosed
EP-0018825-A1 A process for the identification of bacteria and a kit of reagents for use in this process NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1980-11-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198254-A1 Polyamide analogs CYP51A1, HDAC6, ERG28 LTA4H 1790/4885TERT 4086/4885DPP8 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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