SCHEMBL8366013

SCHEMBL8366013

C=CCOc1ccccc1OC(=O)C1CCC(OC)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LIG1 P18858 1/20 0.42
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
ADRB2 P07550 2/20 0.38
ADRB1 P08588 2/20 0.38
SLC22A1 O15245 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
HTR1A P08908 1/20 0.38
CYP2D6 P10635 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
HPGD P15428 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8366016 0.82 SMN1; SMN2 (0.46) POLBKMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL8361960 0.80 L3MBTL1 (0.51) POLBMEN1KMT2ARAB9AL3MBTL1
SCHEMBL10596806 0.75 LIG1 (0.47) POLBMEN1KMT2ARAB9ALIG1
SCHEMBL16756212 0.74 L3MBTL1 (0.70) POLBMEN1KMT2ARAB9AL3MBTL1
SCHEMBL9749313 0.73 LIG1 (0.54) MEN1KMT2ALIG1KDM4ENPC1
SCHEMBL4123709 0.73 POLB (0.67) POLBMEN1KMT2ARAB9AL3MBTL1
SCHEMBL29168887 0.73 LIG1 (0.57) POLBMEN1KMT2ALIG1KDM4E
SCHEMBL29168888 0.72 LIG1 (0.55) POLBMEN1KMT2ALIG1KDM4E
SCHEMBL31321655 0.72 HPGD (0.54) POLBMEN1KMT2ARAB9AL3MBTL1
SCHEMBL7924944 0.71 LIG1 (0.51) MEN1KMT2ALIG1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721602-B1 RETARDATION LAYER HAVING A DISPERSION ADAPTED TO THE ACTIVE LIQUID-CRYSTALLINE CELL AKZO NOBEL NV (NL) 1999-10-27 EP disclosed
US-5760859-A Retardation layer having a dispersion adapted to the active liquid-crystalline cell AKZO NOBEL NV (NL) 1998-06-02 US disclosed
EP-0721602-A1 RETARDATION LAYER HAVING A DISPERSION ADAPTED TO THE ACTIVE LIQUID-CRYSTALLINE CELL Akzo Nobel N.V. (NL) 1996-07-17 EP disclosed
WO-1995009379-A1 RETARDATION LAYER HAVING A DISPERSION ADAPTED TO THE ACTIVE LIQUID-CRYSTALLINE CELL AKZO NOBEL N.V. (NL) 1995-04-06 WO disclosed