Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371524 | 0.79 | RXFP1 (0.54) | MAPTMAP2PRNPCYP1A2CYP2C9 | |
| SCHEMBL14486519 | 0.67 | CA12 (0.44) | MAPTPRKACAPRNPCYP1A2CYP2C9 | |
| SCHEMBL28557466 | 0.66 | SRC (0.46) | GPR35MAPTSRCPRKACAPRKACG | |
| SCHEMBL1252252 | 0.63 | GPR35 (0.49) | GPR35MAPTPKMPRNPCYP1A2 | |
| SCHEMBL10411387 | 0.63 | LDHA (0.39) | GPR35PKMEIF4A3MEN1KMT2A | |
| SCHEMBL27372701 | 0.63 | RXFP1 (0.63) | GPR35MAPTPRNPCYP1A2CYP2C9 | |
| SCHEMBL21465541 | 0.62 | MAPT (0.57) | MAPTPKMPRNPCYP1A2CYP2C9 | |
| SCHEMBL1122596 | 0.62 | ALDH1A1 (0.68) | MAPTCYP1A2NPSR1LMNAMEN1 | |
| SCHEMBL31025896 | 0.61 | GPR35 (0.46) | GPR35PKMPRNPCYP1A2CYP2C9 | |
| SCHEMBL6179303 | 0.59 | KDM4E (0.49) | GPR35EIF4A3GPR17MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999050438-A2 | CHROMOGENIC INDOLE DERIVATIVES | INALCO S.P.A. (IT) | 1999-10-07 | — | — | WO | disclosed |