Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349522 | 0.95 | CPB1 (0.45) | CTSLCTSBCTSKCPB1CPB2 | |
| SCHEMBL6325305 | 0.94 | CPB1 (0.43) | CTSLCTSBCTSKCPB1CPB2 | |
| SCHEMBL6327080 | 0.89 | CPB1 (0.48) | CTSLCTSBCTSKCPB1CPB2 | |
| SCHEMBL6404005 | 0.89 | CPB1 (0.48) | CTSLCTSBCTSKCPB1CPB2 | |
| SCHEMBL8364526 | 0.89 | CTSK (0.46) | CTSLCTSBCTSKHSD11B1DPP4 | |
| SCHEMBL8349084 | 0.89 | CTSL (0.46) | CTSLCTSBCTSKHSD11B1DPP4 | |
| SCHEMBL8347734 | 0.89 | CTSL (0.46) | CTSLCTSBCTSKCPB1CPB2 | |
| SCHEMBL6324698 | 0.83 | CTSL (0.46) | CTSLCTSBCTSKCPB2HSD11B1 | |
| SCHEMBL6324935 | 0.83 | CTSL (0.46) | CTSLCTSBCTSKCPB1CPB2 | |
| SCHEMBL6328692 | 0.82 | CTSL (0.47) | CTSLCTSBCTSKCPB2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003061653-A1 | 3-(IMIDAZOLYL)-2-AMINOPROPANOIC ACIDS FOR USE AS TAFI-A INHIBITORS FOR THE TREATMENT OF THROMBOTIC DISEASES | PFIZER LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |