Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375977 | 0.80 | THRA (0.49) | THRATHRBPPARAAKR1B10AKR1B1 | |
| SCHEMBL28448006 | 0.79 | PPARA (0.44) | THRATHRBPPARAAKR1B10AKR1B1 | |
| SCHEMBL1685287 | 0.73 | TRPV1 (0.54) | HSD17B10THRATHRBTRPV1APP | |
| SCHEMBL1685289 | 0.73 | TRPV1 (0.54) | HSD17B10THRATHRBTRPV1APP | |
| SCHEMBL2022838 | 0.71 | ESR1 (0.43) | APPMEN1ALDH1A1KMT2AAKR1B10 | |
| SCHEMBL541542 | 0.71 | ESR1 (0.43) | APPMEN1ALDH1A1KMT2AAKR1B10 | |
| SCHEMBL7398707 | 0.71 | TSHR (0.40) | TSHRHSD17B10MGLLMEN1KMT2A | |
| SCHEMBL30400690 | 0.71 | PPARA (0.50) | TSHRHSD17B10PPARAALDH1A1 | |
| SCHEMBL27395351 | 0.70 | MEN1 (0.41) | TSHRTRPV1MEN1ALDH1A1KMT2A | |
| SCHEMBL11306935 | 0.70 | EGFR (0.41) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999036049-A1 | PHOTOSTABLE UV ABSORBENT CONTAINING α-CYANO CINNAMYL MOIETY | ISP INVESTMENTS INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| US-5830441-A | SUNSCREEN AGENTS | ISP INVESTMENTS INC. (US) | 1998-11-03 | — | — | US | disclosed |