Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248143 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL6888482 | 0.91 | ALDH1A1 (0.48) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL18127624 | 0.90 | ALDH1A1 (0.44) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL28583742 | 0.88 | CA1 (0.44) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL386476 | 0.88 | ALDH1A1 (0.68) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL18127622 | 0.88 | LMNA (0.45) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL739850 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL28838568 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL181910 | 0.84 | MMP1 (0.45) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL11212816 | 0.83 | LMNA (0.55) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |