Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.47 |
| ▸ | CCR4 | P51679 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366687 | 0.90 | CCR2 (0.53) | CCR2PTGER4MALT1 | |
| SCHEMBL8368076 | 0.90 | CCR2 (0.47) | CCR2CCR4APLNRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8368081 | 0.89 | CCR2 (0.52) | CCR2PTGER4MALT1 | |
| SCHEMBL8366452 | 0.79 | RPA1 (0.50) | MEN1KMT2AMALT1TP53 | |
| SCHEMBL8364557 | 0.77 | MALT1 (0.42) | CCR2LMNAMALT1TP53 | |
| SCHEMBL8042589 | 0.75 | CNR2 (0.65) | — | |
| SCHEMBL8369823 | 0.74 | NPBWR1 (0.45) | MEN1KMT2AMALT1 | |
| SCHEMBL8366708 | 0.73 | RPA1 (0.65) | CCR2GAAMALT1 | |
| SCHEMBL8364849 | 0.72 | RPA1 (0.53) | CCR2MEN1KMT2AMALT1 | |
| SCHEMBL8368094 | 0.70 | HDAC3 (0.50) | GAAMALT1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |