Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366687 | 0.91 | CCR2 (0.53) | CCR2PTGER4MALT1CYP2C9PPARG | |
| Hydrochloric Acid SCHEMBL8368081 | 0.90 | CCR2 (0.52) | CCR2PTGER4MALT1CYP2C9PPARG | |
| SCHEMBL8366606 | 0.90 | CCR2 (0.47) | CCR2MEN1KMT2AATMPTGER4 | |
| SCHEMBL8369218 | 0.78 | RPA1 (0.51) | MEN1KMT2AMALT1TP53LMNA | |
| SCHEMBL8369089 | 0.76 | CNR2 (0.44) | MALT1TP53LMNAMARS1TSHR | |
| SCHEMBL8042589 | 0.76 | CNR2 (0.65) | — | |
| SCHEMBL8369156 | 0.74 | NPBWR1 (0.46) | MEN1KMT2AMALT1MARS1 | |
| SCHEMBL8366708 | 0.73 | RPA1 (0.65) | CCR2MALT1MARS1 | |
| SCHEMBL8364849 | 0.72 | RPA1 (0.53) | CCR2MEN1KMT2AMALT1 | |
| SCHEMBL8368094 | 0.71 | HDAC3 (0.50) | MALT1TP53MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |