Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 8/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RGS12 | O14924 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649350 | 0.85 | AKR1C2 (0.67) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL8366327 | 0.82 | PTGDR2 (0.54) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL8367857 | 0.82 | KDM4E (0.46) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL18271503 | 0.81 | PLA2G2A (0.56) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL7907419 | 0.80 | AKR1C2 (0.51) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL8367878 | 0.79 | EGFR (0.45) | AKR1C2AKR1C3LMNAMEN1MAPT | |
| SCHEMBL8366206 | 0.76 | KDM4E (0.55) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL10876035 | 0.75 | AKR1C3 (0.76) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL18271569 | 0.75 | AKR1C3 (0.64) | AKR1C2AKR1C3LMNACYP1A2CYP2C9 | |
| SCHEMBL31224051 | 0.75 | ALDH1A1 (0.50) | NPSR1MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958924-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS, RESTENOSIS, ANTICOALUGANTS, RESPIRATORY SYSTEM DISORDERS | SYNTHELABO (FR) | 1999-09-28 | — | — | US | disclosed |