SCHEMBL836734

SCHEMBL836734

OCC1OC(O)C(CO)OC1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
LGALS1 P09382 2/20 0.40
LGALS3 P17931 2/20 0.40
LGALS9 O00182 1/20 0.40
LGALS8 O00214 1/20 0.40
SLC2A1 P11166 1/20 0.33
GBA1 P04062 1/20 0.33
TXNRD1 Q16881 1/20 0.33
TXNRD3 Q86VQ6 1/20 0.33
TXNRD2 Q9NNW7 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA12 O43570 3/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA9 Q16790 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12801824 1.00 LMNA (0.42) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL15142 0.96
SCHEMBL18457024 0.94 LMNA (0.39) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL20115301 0.94 LMNA (0.39) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL19055971 0.94 LMNA (0.39) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL24103701 0.94 LMNA (0.39) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL19055972 0.94 LMNA (0.39) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL18904585 0.84 ALDH1A1 (0.33) LMNAALDH1A1TSHRTDP1LGALS1
SCHEMBL28456182 0.83
SCHEMBL19255677 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102770469-B Method for producing water-absorbing polymer particles having improved color stability BASF SE 2015-04-15 CN claimed
US-8497337-B2 Process for producing water-absorbing polymer particles with improved color stability BASF SE (DE) 2013-07-30 US claimed
US-20110121230-A1 Process for Producing Water-Absorbing Polymer Particles with Improved Color Stability BASF SE (DE) 2011-05-26 US claimed
EP-4263558-B1 MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1 JANSSEN PHARMACEUTICA NV (BE) 2025-02-12 EP disclosed
US-12092644-B2 Kits comprising aldehydes to reduce artifacts in analyzing glycans released from glycoproteins or glycopeptides AGILENT TECHNOLOGIES, INC. (US) 2024-09-17 US disclosed
EP-3500842-B1 USE OF MILD ELECTROPHILES TO REDUCE ARTIFACTS IN ANALYZING GLYCANS RELEASED FROM GLYCOPROTEINS OR GLYCOPEPTIDES AGILENT TECHNOLOGIES INC (US) 2024-04-10 EP disclosed
US-20240083890-A1 MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1 JANSSEN PHARMACEUTICA NV (BE) 2024-03-14 US disclosed
EP-4263558-A1 MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1 JANSSEN Pharmaceutica NV (BE) 2023-10-25 EP disclosed
WO-2022129331-A1 MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1 JANSSEN PHARMACEUTICA NV (BE) 2022-06-23 WO disclosed
US-11035862-B2 Use of mild electrophiles to reduce artifacts in analyzing glycans released from glycoproteins or glycopeptides AGILENT TECHNOLOGIES, INC. (US) 2021-06-15 US disclosed
US-11035862-B2 Use of mild electrophiles to reduce artifacts in analyzing glycans released from glycoproteins or glycopeptides AGILENT TECHNOLOGIES, INC. (US) 2021-06-15 US disclosed
WO-2010132839-A2 AMINOGLYCOSIDE DOSING REGIMENS ACHAOGEN, INC. (US) 2010-11-18 WO disclosed
WO-2010132760-A1 ANTIBACTERIAL DERIVATIVES OF TOBRAMYCIN ACHAOGEN, INC. (US) 2010-11-18 WO disclosed
WO-2010132759-A1 ANTIBACTERIAL DERIVATIVES OF DIBEKACIN ACHAOGEN, INC. (US) 2010-11-18 WO disclosed
US-20100104515-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS GORDIAN PHARMA LIMITED (GB) 2010-04-29 US disclosed
WO-2010042850-A1 ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS ACHAOGEN, INC. (US) 2010-04-15 WO disclosed
US-20080308426-A1 Electrochemical Method for the Production of Betulin Aldehyde REGENTS OF THE UNIVERSITY OF MINNESOTA 2008-12-18 US disclosed
WO-2008046232-A1 AZIRIDINE ALDEHYDES, AZIRIDINE-CONJUGATED AMINO DERIVATIVES, AZIRIDINE-CONJUGATED BIOMOLECULES AND PROCESSES FOR THEIR PREPARATION YUDIN ANDREI K (CA) 2008-04-24 WO disclosed
WO-2007074344-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS MORVUS TECHNOLOGY LIMITED (GB) 2007-07-05 WO disclosed
WO-2004037159-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM OBETHERAPY BIOTECHNOLOGY (FR) 2004-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104515-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS DERA, HOGA1, ALDOA LMNA 763/4885ALDH1A1 78/4885TSHR 4884/4885
US-20240083890-A1 MACROCYCLIC BRANCHED 3-FLUORO-BUT-3-ENAMIDES AS INHIBITORS OF MCL-1 MCL1, BCL3, BCL2L1 LMNA 743/4885ALDH1A1 409/4885TSHR 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.