SCHEMBL8367644

SCHEMBL8367644

CC(C)(c1ccccc1)c1cc(S(=O)(=O)O)cc(O)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 3/20 0.40
NR3C2 P08235 2/20 0.40
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
CYP3A4 P08684 1/20 0.40
NSD2 O96028 3/20 0.39
DUSP3 P51452 2/20 0.39
PTPN5 P54829 2/20 0.39
CASP6 P55212 2/20 0.39
PTPN11 Q06124 2/20 0.39
CASP7 P55210 1/20 0.39
APEX1 P27695 1/20 0.37
HSD17B10 Q99714 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
CNR1 P21554 3/20 0.37
CNR2 P34972 3/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8369674 0.92 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1
SCHEMBL8369689 0.84 NR3C2 (0.38) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1
SCHEMBL8365847 0.84 CNR1 (0.38) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1
SCHEMBL8369552 0.80 ESR1 (0.43) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1
SCHEMBL8369557 0.79 CA2 (0.43) SMN1; SMN2ALDH1A1NSD2DUSP3PTPN5
SCHEMBL8516948 0.77 ALDH1A1 (0.38) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1
SCHEMBL8367502 0.77 ESR1 (0.44) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1
SCHEMBL8369553 0.77 ESR2 (0.44) TSHRALDH1A1NR3C2ESR1ESR2
SCHEMBL8367500 0.76 CYP3A4 (0.40) TSHRALDH1A1NR3C2ESR1ESR2
SCHEMBL8369784 0.76 ESR1 (0.40) TSHRSMN1; SMN2ALDH1A1NR3C2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed