Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 13/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855741 | 0.74 | F2 (0.48) | F2PRSS1PRSS2PRSS3ELANE | |
| SCHEMBL12125050 | 0.69 | KDM4E (0.43) | MAPT | |
| SCHEMBL6760708 | 0.66 | — | — | |
| SCHEMBL13869172 | 0.63 | CYP19A1 (0.47) | PKMKEAP1NFE2L2MAPT | |
| SCHEMBL2760277 | 0.62 | MAPT (0.55) | KEAP1NFE2L2METAP2MAPT | |
| SCHEMBL1474470 | 0.61 | ADRB3 (0.43) | KEAP1NFE2L2MAPT | |
| SCHEMBL13303941 | 0.61 | PTGS1 (0.47) | KEAP1NFE2L2 | |
| SCHEMBL24481325 | 0.60 | MAPT (0.41) | KEAP1NFE2L2MAPT | |
| SCHEMBL2068498 | 0.60 | KEAP1 (0.65) | KEAP1NFE2L2 | |
| SCHEMBL29904739 | 0.60 | KEAP1 (0.65) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048155-A1 | THROMBIN INHIBITORS | UNIVERSITY OF LJUBLJANA (SI) | 2003-06-12 | — | — | WO | disclosed |