Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368026 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 | |
| SCHEMBL10971917 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2HPGDPKMMAPTALDH1A1 | |
| SCHEMBL8395979 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 | |
| SCHEMBL11052170 | 0.77 | L3MBTL1 (0.59) | SMN1; SMN2HPGDMAPTALDH1A1GAA | |
| SCHEMBL8004775 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 | |
| SCHEMBL9804683 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 | |
| SCHEMBL9804687 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 | |
| SCHEMBL14359273 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 | |
| SCHEMBL11327733 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDPKMCYP1A2MAPT | |
| SCHEMBL8007278 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDPKMCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11001458-A | — | — | None | — | — | JP | disclosed |
| JP-H111458-A | BENZOPHENONE HYDRAZONE DERIVATIVE AND INSECTICIDE | NIPPON BAYERAGROCHEM KK | 1999-01-06 | — | — | JP | disclosed |