Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804687 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL9403700 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL8682896 | 0.81 | LMNA (0.60) | SMN1; SMN2CYP1A2MEN1KMT2APKM | |
| SCHEMBL260379 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AALOX12HTT | |
| SCHEMBL260380 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AALOX12HTT | |
| SCHEMBL8395979 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL10971917 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AALOX12HTT | |
| SCHEMBL11052170 | 0.76 | L3MBTL1 (0.59) | SMN1; SMN2MEN1KMT2AALOX12HTT | |
| SCHEMBL8368026 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL8368024 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP1A2ABCB11CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983755-A | Nematocides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |