Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | MARS1 | P56192 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369874 | 0.91 | RPA1 (0.61) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369627 | 0.90 | CNR2 (0.44) | RPA1HDAC6MARS1SMPD1CNR2 | |
| SCHEMBL8369218 | 0.88 | RPA1 (0.51) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369248 | 0.87 | CNR2 (0.50) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8368110 | 0.81 | CNR2 (0.49) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369654 | 0.81 | MARS1 (0.49) | RPA1MARS1CNR2PPP1CACNR1 | |
| SCHEMBL8046115 | 0.79 | RPA1 (0.63) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5903036 | 0.79 | CNR2 (0.59) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8368933 | 0.78 | RPA1 (0.51) | RPA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8366452 | 0.78 | RPA1 (0.50) | RPA1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |