Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368458 | 0.87 | LMNA (0.50) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL20398212 | 0.86 | SMN1; SMN2 (0.52) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL28298076 | 0.86 | ALDH1A1 (0.50) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL307639 | 0.86 | CYP1A2 (0.43) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL18525261 | 0.86 | ALDH1A1 (0.41) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL5391790 | 0.86 | TSHR (0.49) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL5410176 | 0.85 | ALDH1A1 (0.55) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL10661800 | 0.85 | SMN1; SMN2 (0.73) | LMNATSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL30292273 | 0.85 | SMN1; SMN2 (0.50) | LMNATSHRCHRM2CHRM1ALOX15 | |
| SCHEMBL5672371 | 0.84 | TP53 (0.51) | LMNASMN1; SMN2L3MBTL1ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672720-B1 | Formaldehyde-free binding, impregnating or coating composition for fibreous sheets | BASF AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| US-5536766-A | ACID, ANHYDRIDE ACRYLIC POLYMER; TRIAZINE, BENZENE, CYCLOHEXANE POLYOL CROSSLINKING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | disclosed |
| EP-0672720-A1 | Formaldehyde-free binding, impregnating or coating composition for fibreous sheets | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |
| US-4839124-A | Reduction of carboxyl end groups in polyester fibers with lactim ethers | ALLIED-SIGNAL INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4129611-A | Thermoplastic polyurethanes of mixtures of hard and soft thermoplast polymers | MOBAY CHEMICAL CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |