SCHEMBL8368642

SCHEMBL8368642

CCCCCCCO[Si](C)(CCCCCC)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.33
CA1 P00915 7/20 0.32
CA2 P00918 7/20 0.32
LPAR3 Q9UBY5 6/20 0.32
CA9 Q16790 6/20 0.32
LPAR2 Q9HBW0 5/20 0.32
CA12 O43570 3/20 0.32
CA7 P43166 3/20 0.32
CA14 Q9ULX7 3/20 0.32
LPAR1 Q92633 2/20 0.32
CA3 P07451 2/20 0.32
CA4 P22748 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28518202 0.94 LMNA (0.33) LMNATHRBALDH1A1TDP1MEN1
SCHEMBL29682053 0.92 LMNA (0.36) LMNATHRBALDH1A1TDP1TSHR
SCHEMBL29073241 0.91 LMNA (0.32) LMNA
SCHEMBL28424236 0.89 THRB (0.38) THRBALDH1A1TDP1TSHRMEN1
SCHEMBL27996182 0.89 LMNA (0.41) LMNATHRBALDH1A1TSHRMEN1
Fluoride SCHEMBL28152818 0.87 LMNA (0.40) LMNATHRBALDH1A1TSHRMEN1
SCHEMBL15515517 0.86 DNM1 (0.38) LMNAALDH1A1TSHRMEN1HTT
SCHEMBL27777833 0.85 THRB (0.35) LMNATHRBALDH1A1TDP1TSHR
SCHEMBL27904666 0.85 THRB (0.38) LMNATHRBALDH1A1TDP1TSHR
SCHEMBL11332073 0.85 THRB (0.38) LMNATHRBALDH1A1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233916-A Long carbon chain sulfur-containing silane coupling agent, and preparation method and application thereof 南京曙光精细化工有限公司 2020-06-05 CN disclosed
EP-0576413-B1 Electron donors for improved olefin polymerization FINA TECHNOLOGY (US) 1999-01-13 EP disclosed