Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.51 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368881 | 0.99 | S100A4 (0.49) | S100A4MALT1MAPTALDH1A1ACP1 | |
| SCHEMBL8368796 | 0.93 | S100A4 (0.58) | S100A4MALT1MAPTALDH1A1ACP1 | |
| SCHEMBL1917262 | 0.85 | S100A4 (0.45) | S100A4MALT1MAPTALDH1A1ACP1 | |
| SCHEMBL1918660 | 0.83 | S100A4 (0.45) | S100A4MALT1MAPTALDH1A1ACP1 | |
| SCHEMBL8367269 | 0.81 | MALT1 (0.60) | S100A4MALT1ALDH1A1LMNAMEN1 | |
| SCHEMBL8368655 | 0.77 | MALT1 (0.41) | S100A4MALT1MAPTALDH1A1BLM | |
| SCHEMBL8369483 | 0.76 | S100A4 (0.61) | S100A4MALT1MAPTBLML3MBTL1 | |
| SCHEMBL8368658 | 0.76 | S100A4 (0.44) | S100A4MALT1MAPTALDH1A1BLM | |
| SCHEMBL8370510 | 0.75 | S100A4 (0.46) | S100A4MAPTALDH1A1BLML3MBTL1 | |
| SCHEMBL8367439 | 0.75 | NLRP3 (0.40) | MALT1BLMMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |