SCHEMBL8369

SCHEMBL8369

[O]c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30500259 1.00
SCHEMBL28796339 0.97
Benzene SCHEMBL27526163 0.97 LMNA (0.48)
Pyrimidine SCHEMBL27362946 0.87 CYP2A6 (0.42)
SCHEMBL27653492 0.83 NOS3 (0.39)
SCHEMBL2174187 0.73 KDM4E (0.71)
Dipyridyl SCHEMBL28302286 0.71 KDM4E (0.93)
SCHEMBL21358014 0.71 LMNA (0.46)
SCHEMBL4015315 0.69 ALDH1A1 (0.67)
SCHEMBL4653 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 30742 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
EP-4399206-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. (US) 2024-07-17 EP claimed
US-12029739-B2 SHP2 inhibitor and use thereof KANAPH THERAPEUTICS INC. (KR) 2024-07-09 US claimed
CN-115023425-B Pesticidally active heterocyclic derivatives with sulfur containing substituents 先正达农作物保护股份公司 2024-07-09 CN claimed
WO-2024126677-A1 MUTATED LACTO-N-BIOSIDASE DSM IP ASSETS B.V. (NL) 2024-06-20 WO claimed
WO-2024126388-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2024-06-20 WO claimed
US-20240199600-A1 CONDENSED HETEROCYCLIC COMPOUND HAVING A SULFONAMIDE GROUP OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT COMPRISING THE COMPOUND OR THE SALT THEREOF, AND METHOD FOR USING THE COMPOUND OR THE SALT THEREOF, THE INSECTICIDE, OR THE CONTROL AGENT NIHON NOHYAKU CO., LTD. (JP) 2024-06-20 US claimed
CN-118201914-A 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors 雷多纳治疗公司 2024-06-14 CN claimed
US-20240189306-A1 SHP2 INHIBITOR AND USE THEREOF KANAPH THERAPEUTICS INC. (KR) 2024-06-13 US claimed
EP-4149933-B1 NEW TRIAZOLYL DERIVATIVES AS GABA A ALPHA5 PAM HOFFMANN LA ROCHE (CH) 2024-06-12 EP claimed
EP-0000176-B1 PYRIDYLOXY-PHENOXY-ALKANOIC ACID DERIVATIVES , PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES OR PLANT GROWTH REGULATORS CIBA-GEIGY AG (CH) 1981-09-16 EP claimed
EP-0007605-A1 A process for inverting the configuration in optically active compounds and optically active intermediate compounds and their salts required therefor CIBA-GEIGY AG (CH) 1980-02-06 EP claimed
US-4172198-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-10-23 US claimed
US-4119777-A BY OXIDATION OF A THIOAMIDE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1978-10-10 US claimed
US-4045556-A ANTIDEPRESSANTS, PYSCHOSTIMULANTS; SILYLATION SCHWERTNER EBERHARD 1977-08-30 US claimed
US-4025553-A Production of o-hydroxybenzyl alcohols SHIONOGI & CO., LTD. (JA) 1977-05-24 US claimed
US-4017488-A Process for preparing 7β-acylamino-7α-alkoxycephalosporins SANKYO COMPANY LIMITED (JA) 1977-04-12 US claimed
US-4012521-A CHLOROMETHYLAROYL SULFIDES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-03-15 US claimed
US-4011214-A 3-(MORPHOLINOALKOXYIMINOMETHYL)CEPHEM COMPOUNDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-03-08 US claimed
US-3954776-A ANTIARRHYTHMICS, ANAESTHETICS, ANALGESICS, ANTISECRETORY AGENTS YOSHITOMI PHARMECEUTICAL INDUSTRIES, LTD. (JA) 1976-05-04 US claimed