Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157725 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTHSD17B10TSHRHTT | |
| SCHEMBL9152213 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10TSHRHTT | |
| SCHEMBL8369447 | 0.81 | AR (0.51) | LMNAARCA12CA9HPGD | |
| SCHEMBL4112149 | 0.81 | KDM4E (0.50) | ALDH1A1MAPTHSD17B10TSHRHTT | |
| SCHEMBL8210777 | 0.81 | KMT2A (0.50) | ALDH1A1MAPTHSD17B10TSHRLMNA | |
| SCHEMBL23118890 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHSD17B10TSHRHTT | |
| SCHEMBL8364405 | 0.81 | KDM4E (0.55) | ALDH1A1MAPTHSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL8367852 | 0.80 | AR (0.50) | LMNAARCA12CA9HPGD | |
| SCHEMBL8368811 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9766147 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MAPTHSD17B10TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983607-A | ANTISEROTONINERGIC ACTIVITY | SYNTHELABO (FR) | 1991-01-08 | — | — | US | disclosed |