Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.58 |
| ▸ | TUBB | P07437 | 3/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799524 | 0.94 | HTR2A (0.60) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7424861 | 0.90 | HTR2A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10665105 | 0.86 | HTR2A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27570422 | 0.84 | TNKS2 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5514786 | 0.82 | PTGS2 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10736060 | 0.82 | AOC3 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4464142 | 0.81 | HTR2A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL23266383 | 0.81 | TUBB1 (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10772012 | 0.81 | PTGS2 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10774727 | 0.81 | PTGS2 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8073357-A | — | — | None | — | — | JP | disclosed |
| EP-0710482-B1 | Therapeutic agent for myocardial ischemic damages or reperfusion injuries | KOWA CO (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5824675-A | Preventive and therapeutic agent for kidney diseases | KOWA CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |
| EP-0786254-A1 | PREVENTIVE OR REMEDY FOR KIDNEY DISEASES | KOWA CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |
| US-5602123-A | USING A BIS/PHENYLALKYL/PIPERAZINE SALT | KOWA CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0710482-A2 | Therapeutic agent for myocardial ischemic damages or reperfusion injuries | KOWA COMPANY, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| JP-H0873357-A | THERAPEUTIC AGENT FOR SENILE DEMENTIA OR ALZHEIMER'S DISEASE | KOWA CO | 1996-03-19 | — | — | JP | disclosed |
| EP-0541798-B1 | NEW DIAMINE COMPOUND AND BRAIN PROTECTING AGENT CONTAINING THE SAME | KOWA CO (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5389630-A | Diamine compound and brain protecting agent containing the same | KOWA CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0541798-A1 | NEW DIAMINE COMPOUND AND BRAIN PROTECTING AGENT CONTAINING THE SAME | Kowa Company Ltd. (JP) | 1993-05-19 | — | — | EP | disclosed |