SCHEMBL8370410

SCHEMBL8370410

Cc1cc(O)c(S(=O)(=O)O)cc1C(CC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 3/20 0.36
CHRM2 P08172 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
HRH1 P35367 2/20 0.36
MAPT P10636 2/20 0.36
ESR1 P03372 1/20 0.36
CHRM4 P08173 1/20 0.36
KCNE1 P15382 1/20 0.36
PTGS1 P23219 1/20 0.36
HRH2 P25021 1/20 0.36
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517199 0.90 ALDH1A1 (0.41) TRPA1ALDH1A1GAAHTTHSD17B10
SCHEMBL8365934 0.90 TRPA1 (0.41) TRPA1ALDH1A1GAAHTTHSD17B10
SCHEMBL8370434 0.85 TRPA1 (0.40) TRPA1ALDH1A1HTTLMNACHRM2
SCHEMBL8367596 0.82 TYR (0.46) ALDH1A1GAAHTTHSD17B10LMNA
SCHEMBL8367578 0.81 TRPA1 (0.38) TRPA1ALDH1A1GAAHSD17B10LMNA
SCHEMBL8367836 0.80 TYR (0.44) TRPA1ALDH1A1GAAHTTHSD17B10
SCHEMBL8365997 0.80 TRPA1 (0.38) TRPA1ALDH1A1LMNACHRM2CHRM5
SCHEMBL8370499 0.80 TRPA1 (0.38) TRPA1GAALMNACHRM2CHRM5
SCHEMBL8516728 0.80 LMNA (0.40) TRPA1GAAHTTHSD17B10LMNA
SCHEMBL8370476 0.80 TRPA1 (0.40) TRPA1LMNACHRM2CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed