Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374209 | 0.85 | GABRA1 (0.56) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 | |
| SCHEMBL10841494 | 0.85 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4CA1CA2 | |
| SCHEMBL1133364 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 | |
| SCHEMBL28201284 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 | |
| SCHEMBL30520271 | 0.78 | CYP3A4 (0.63) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 | |
| SCHEMBL2169198 | 0.78 | CYP3A4 (0.52) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 | |
| SCHEMBL20145 | 0.78 | CYP3A4 (0.63) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 | |
| SCHEMBL10613158 | 0.77 | GABRA1 (0.75) | GABRA1GABRB2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL9965047 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MEN1HSP90AA1KMT2AATM | |
| SCHEMBL30390691 | 0.76 | GABRA1 (0.52) | GABRA1GABRB2CYP3A4ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1276787-A | Substd. N-aryl-O-aryloxyalkyl carbamates and their use as herbicides | BAYER AG (DE) | 2000-12-13 | — | — | CN | disclosed |
| WO-1999065869-A1 | SUBSTITUTED N-ARYL-O-ALKYL-CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-23 | — | — | WO | disclosed |
| EP-0217787-A4 | AMIDINOUREA PROCESS AND PHARMACEUTICAL COMPOSITION. | RORER INTERNAT OVERSEAS INC (US) | 1988-07-21 | — | — | EP | disclosed |
| EP-0217787-A1 | AMIDINOUREA PROCESS AND PHARMACEUTICAL COMPOSITION | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1987-04-15 | — | — | EP | disclosed |
| WO-1986004935-A1 | AMIDINOUREA PROCESS AND PHARMACEUTICAL COMPOSITION | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1986-08-28 | — | — | WO | disclosed |