Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933174 | 0.83 | KMT2A (0.48) | ALDH1A1KMT2AATMMAPTMEN1 | |
| SCHEMBL3498713 | 0.83 | CDK5 (0.38) | ALDH1A1KMT2AATMMAPTMEN1 | |
| SCHEMBL15505879 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2AATMMEN1HSP90AA1 | |
| SCHEMBL8370425 | 0.77 | GABRA1 (0.47) | ALDH1A1KMT2AATMMEN1HSP90AA1 | |
| SCHEMBL6050004 | 0.74 | KMT2A (0.43) | ALDH1A1KMT2AATMMAPTMEN1 | |
| SCHEMBL24052991 | 0.73 | CYP3A4 (0.35) | ALDH1A1KMT2AMAPTMEN1HSP90AA1 | |
| SCHEMBL14094866 | 0.73 | KMT2A (0.42) | ALDH1A1KMT2AATMMAPTMEN1 | |
| SCHEMBL19336624 | 0.73 | GSK3A (0.33) | ALDH1A1KMT2AMAPTHSP90AA1CDK1 | |
| SCHEMBL4755413 | 0.73 | ATM (0.50) | ALDH1A1KMT2AATMMAPTMEN1 | |
| SCHEMBL14256812 | 0.73 | KMT2A (0.42) | ALDH1A1KMT2AATMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790724-B2 | c-fms kinase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-07 | — | — | US | disclosed |