SCHEMBL8370468

SCHEMBL8370468

CC(c1ccccc1C(C)(C)c1ccccc1)c1cccc(S(=O)(=O)O)c1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.36
ESR2 Q92731 2/20 0.35
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR1 P03372 1/20 0.35
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
NR3C2 P08235 3/20 0.33
HSD11B1 P28845 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
MMP14 P50281 1/20 0.32
MMP16 P51512 1/20 0.32
PGAM1 P18669 1/20 0.31
CA2 P00918 2/20 0.31
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370535 0.82 TYR (0.36) CYP1A2CYP3A4ALDH1A1MMP1MMP2
SCHEMBL8369682 0.80 ESR1 (0.41) CYP1A2ESR2CYP3A4ALDH1A1ESR1
SCHEMBL8367583 0.79 TYR (0.41) CYP1A2CYP3A4ALDH1A1MMP1MMP2
SCHEMBL8365824 0.79 TYR (0.42) CYP1A2CYP3A4ALDH1A1MMP1MMP2
SCHEMBL8370555 0.76 TYR (0.41) CYP1A2ESR2CYP3A4ALDH1A1ESR1
SCHEMBL8370471 0.75 ESR2 (0.36) CYP1A2ESR2CYP3A4ALDH1A1ESR1
SCHEMBL8370537 0.73 TYR (0.40) CYP1A2ESR2CYP3A4ALDH1A1ESR1
SCHEMBL10775084 0.72 GABRA1 (0.53) CYP1A2ESR2CYP3A4ALDH1A1ESR1
SCHEMBL8365989 0.72 TRPA1 (0.40) CYP1A2CYP3A4ALDH1A1LMNAHPGD
SCHEMBL10599648 0.72 CRHBP (0.40) CYP1A2ESR2CYP3A4ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed