Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517156 | 0.94 | NR1H4 (0.45) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7993333 | 0.82 | NR1H4 (0.45) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8516703 | 0.82 | PPARG (0.45) | ALDH1A1MAPTSMN1; SMN2ACHEPPARG | |
| SCHEMBL7008451 | 0.81 | GPR6 (0.43) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8185705 | 0.77 | MEN1 (0.47) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8517477 | 0.76 | PPARG (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAPPARG | |
| SCHEMBL8185689 | 0.76 | NR1H4 (0.46) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7797660 | 0.75 | NR1H4 (0.45) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8184192 | 0.75 | NR1H4 (0.45) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8187880 | 0.74 | NR1H4 (0.45) | NR1H4DHODHALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | claimed |
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |