Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516703 | 0.94 | PPARG (0.45) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8517156 | 0.82 | NR1H4 (0.45) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8370671 | 0.76 | NR1H4 (0.46) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24619874 | 0.75 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ATAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL28676357 | 0.74 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2ATAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL28676356 | 0.74 | MEN1 (0.45) | SMN1; SMN2MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL8516665 | 0.70 | HCRTR1 (0.46) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8436242 | 0.70 | PPARG (0.43) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16088691 | 0.70 | KMT2A (0.61) | PPARGPPARASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8367446 | 0.69 | KCNA5 (0.48) | PPARGPPARAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |