Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517477 | 0.94 | PPARG (0.43) | PPARGPPARAPLK1ALDH1A1IRAK4 | |
| SCHEMBL8370671 | 0.82 | NR1H4 (0.46) | PPARGPPARAACHEALDH1A1MEN1 | |
| SCHEMBL8517156 | 0.76 | NR1H4 (0.45) | PPARGPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL8436242 | 0.72 | PPARG (0.43) | PPARGPPARAPLK1MEN1KMT2A | |
| SCHEMBL16088691 | 0.71 | KMT2A (0.61) | PPARGPPARAPLK1ALDH1A1MEN1 | |
| SCHEMBL8367446 | 0.70 | KCNA5 (0.48) | PPARGPPARAACHEMEN1KMT2A | |
| SCHEMBL7801348 | 0.69 | PPARG (0.68) | PPARGPPARACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7799996 | 0.68 | PPARA (0.89) | PPARGPPARAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8516665 | 0.68 | HCRTR1 (0.46) | PPARGPPARAMEN1KMT2ANPC1 | |
| SCHEMBL24619874 | 0.68 | MEN1 (0.46) | ACHEALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |