Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516525 | 0.92 | KMT2A (0.56) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL7220671 | 0.78 | NR4A1 (0.41) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL4278160 | 0.78 | TAS1R3 (0.55) | DRD2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8370695 | 0.77 | HSD17B2 (0.46) | KMT2AMEN1LMNAMAOACCR2 | |
| SCHEMBL22501405 | 0.77 | GID4 (0.41) | KMT2AMEN1LMNAMAOA | |
| SCHEMBL1881338 | 0.77 | GID4 (0.41) | KMT2AMEN1LMNAMAOA | |
| SCHEMBL35212357 | 0.76 | GPR35 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL18339431 | 0.76 | GPR35 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL35212373 | 0.76 | GPR35 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL1573408 | 0.76 | GPR35 (0.44) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |