SCHEMBL3937549

SCHEMBL3937549

Nc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.51
RAB9A P51151 10/20 0.51
LMNA P02545 1/20 0.51
MEN1 O00255 7/20 0.50
KMT2A Q03164 7/20 0.50
KDM4E B2RXH2 6/20 0.50
MAPT P10636 6/20 0.50
ALDH1A1 P00352 5/20 0.50
CASP1 P29466 4/20 0.50
HPGD P15428 3/20 0.50
CASP7 P55210 3/20 0.50
HSD17B10 Q99714 3/20 0.50
TP53 P04637 2/20 0.50
ALOX15 P16050 2/20 0.50
STAT1 P42224 1/20 0.50
APAF1 O14727 1/20 0.50
POLB P06746 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
GAA P10253 2/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30058950 1.00 NPC1 (0.51) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL508298 0.86 NPC1 (0.65) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL29444885 0.86 NPC1 (0.65) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL9552155 0.85 MEN1 (0.53) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL3217888 0.83 KMT2A (0.63) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL7785471 0.82 MEN1 (0.51) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL6930714 0.82 NPC1 (0.56) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL10441256 0.82 NPC1 (0.56) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL45835 0.81 NPC1 (0.54) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL8370972 0.79 TAAR1 (0.50) NPC1RAB9ALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521693-A Preparation method of UV-resistant flame-retardant waterproof polyurethane resin and high-grade calf leather 兴业皮革科技股份有限公司 2022-12-27 CN claimed
CN-115449570-A Preparation method and application of sulfonated UV-resistant retanning agent based on collagen 兴业皮革科技股份有限公司 2022-12-09 CN claimed
EP-2046279-B1 Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of uv radiation and cosmetic compositions thereof BASF SE (DE) 2014-05-14 EP claimed
US-8221729-B2 Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof BASF SE (DE) 2012-07-17 US claimed
US-20090246154-A1 USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF BASF SE (DE) 2009-10-01 US claimed
EP-2046279-A1 USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF Ciba Holding Inc. (CH) 2009-04-15 EP claimed
WO-2008012304-A1 USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF CIBA HOLDING INC. (CH) 2008-01-31 WO claimed
US-20230329100-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
CN-115521693-A Preparation method of UV-resistant flame-retardant waterproof polyurethane resin and high-grade calf leather 兴业皮革科技股份有限公司 2022-12-27 CN disclosed
CN-115449570-A Preparation method and application of sulfonated UV-resistant retanning agent based on collagen 兴业皮革科技股份有限公司 2022-12-09 CN disclosed
CN-103755690-B Yellowing inhibitor of thermal stability type coumarin flourescent brightener and preparation and application thereof UNIV SHAANXI SCIENCE & TECH 2015-06-17 CN disclosed
CN-104404825-A Preparation method of thermally stable high-yield pulp yellowing inhibitor UNIV SHAANXI SCIENCE & TECH 2015-03-11 CN disclosed
EP-2046279-B1 Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of uv radiation and cosmetic compositions thereof BASF SE (DE) 2014-05-14 EP disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
EP-0388356-A2 Ultraviolet absorbing lenses and methods of making the same CIBA-GEIGY AG (CH) 1990-09-19 EP disclosed
US-4929250-A HALOTRIAZINE DERIVATIVES, QUARTERINARY AMMONIUM SALTS CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329100-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAT1, SLC1A2, SLC18A1 NPC1 3257/4885RAB9A 2664/4885LMNA 2284/4885
US-20090246154-A1 USE OF AMINOPHENYLBENZOTRIAZOLE DERIVATIVES FOR PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE HARMFUL EFFECTS OF UV RADIATION AND COSMETIC COMPOSITIONS THEREOF C9, C5, C3AR1 NPC1 3087/4885RAB9A 3677/4885LMNA 441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.