SCHEMBL837131

SCHEMBL837131

Cc1ccccc1N(O)C(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.46
HPGD P15428 4/20 0.45
KDM4E B2RXH2 1/20 0.45
TSHR P16473 1/20 0.44
NPSR1 Q6W5P4 4/20 0.43
POLB P06746 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HSD11B1 P28845 1/20 0.41
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
HTT P42858 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
PLA2G1B P04054 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11219021 0.82 TRPM8 (0.47) TRPM8HPGDKDM4ETSHRNPSR1
SCHEMBL8187602 0.82 TRPM8 (0.50) TRPM8TSHRALDH1A1KMT2AMEN1
SCHEMBL3807892 0.81 ALDH1A1 (0.51) TRPM8KDM4ENPSR1ALDH1A1KMT2A
SCHEMBL29618443 0.80 TSHR (0.48) TRPM8HPGDKDM4ETSHRNPSR1
SCHEMBL28060297 0.80 NPC1 (0.50) HPGDKDM4ETSHRALDH1A1KMT2A
SCHEMBL28758862 0.80 TSHR (0.48) TRPM8HPGDKDM4ETSHRNPSR1
SCHEMBL27581690 0.79 NPSR1 (0.46) TRPM8HPGDTSHRNPSR1POLB
SCHEMBL8356461 0.78 LMNA (0.45) TRPM8HPGDTSHRNPSR1POLB
SCHEMBL15999740 0.78 NR3C2 (0.49) TRPM8HPGDKDM4ETSHRNPSR1
SCHEMBL3285068 0.78 LMNA (0.51) TRPM8HPGDTSHRNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591194-B Para-functional arylamine compound and synthesis method thereof 山东大学 2023-08-15 CN disclosed
CN-113754575-B Method for synthesizing chiral tryptophan derivative 山东大学 2023-07-18 CN disclosed
CN-113754575-A Method for synthesizing chiral tryptophan derivative 山东大学 2021-12-07 CN disclosed
EP-1607446-B1 ORGANIC/INORGANIC HYBRID MATERIAL, COMPOSITION FOR SYNTHESIZING THE SAME AND PROCESS FOR PRODUCING THE HYBRID MATERIAL SEMICONDUCTOR ENERGY LAB (JP) 2016-09-07 EP disclosed
US-8143423-B2 N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-27 US disclosed
US-8143423-B2 N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-27 US disclosed
US-8143423-B2 N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-27 US disclosed
US-7879257-B2 comprising a metal oxide and a chelating ligand such as 8-quinolinol; material in which an organic group directly connected to a metal oxide develops a coloring property, a light-emitting property, or semiconductivity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-02-01 US disclosed
US-7879257-B2 comprising a metal oxide and a chelating ligand such as 8-quinolinol; material in which an organic group directly connected to a metal oxide develops a coloring property, a light-emitting property, or semiconductivity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-02-01 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20020058200-A1 Positive resist composition FUJI PHOTO FILM CO., LTD. 2002-05-16 US disclosed
WO-2001025783-A1 ANALYTE-BINDING ASSAY REFERENCE DIAGNOSTICS, INC. (US) 2001-04-12 WO disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
US-5684103-A OF AT LEAST ONE BINDER RESIN, A DILUENT MONOMER AND A FILLER JENERIC/PENTRON INCORPORATED (US) 1997-11-04 US disclosed
EP-0763512-A1 AIR BAG GAS GENERATING AGENT OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-03-19 EP disclosed
EP-0742001-A2 Colour stable dental restorative materials JENERIC/PENTRON Incorporated (US) 1996-11-13 EP disclosed
US-5444104-A Dental restorative material based on a polycarbonate dimethacrylate JENERIC/PENTRON, INC. (US) 1995-08-22 US disclosed
EP-0640686-A2 Method for stabilizing glucose 6-phosphate dehydrogenase KYOWA MEDEX CO.LTD. (JP) 1995-03-01 EP disclosed
US-5348475-A Acrylated biscarbonate monomer that cures with light and heat JENERIC/PENTRON INC. (US) 1994-09-20 US disclosed
US-5276068-A Dimethacrylate compounds containing carbonate groups, adhesives, restoration material JENERIC/PENTRON, INC. (US) 1994-01-04 US disclosed