⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454284 | 0.97 | — | — | |
| SCHEMBL20267752 | 0.94 | LMNA (0.38) | — | |
| SCHEMBL2214370 | 0.77 | — | — | |
| SCHEMBL4755274 | 0.76 | — | — | |
| SCHEMBL9721110 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL3929610 | 0.73 | — | — | |
| SCHEMBL16970183 | 0.73 | — | — | |
| SCHEMBL11626728 | 0.73 | — | — | |
| SCHEMBL29222906 | 0.73 | — | — | |
| SCHEMBL31398004 | 0.72 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3881857-B1 | GENERATING GABAERGIC NEURONS IN BRAINS | PENN STATE RES FOUND (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20240091300-A1 | CHEMICAL REPROGRAMMING OF HUMAN GLIAL CELLS INTO NEURONS FOR BRAIN AND SPINAL CORD REPAIR | THE PENN STATE RESEARCH FOUNDATION (US) | 2024-03-21 | — | — | US | disclosed |
| US-11850273-B2 | Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-12-26 | — | — | US | disclosed |
| CN-114874366-B | Multi-center supported metalloporphyrin complex and preparation method thereof, and preparation method of carbon dioxide-based polymer | 中国科学院长春应用化学研究所 | 2023-06-20 | — | — | CN | disclosed |
| CN-114874366-A | Multi-center loaded metalloporphyrin complex and preparation method thereof as well as preparation method of carbon dioxide-based polymer | 中国科学院长春应用化学研究所 | 2022-08-09 | — | — | CN | disclosed |
| CN-114601937-A | Regenerating functional neurons for treatment of disease and injury in the nervous system | 宾夕法尼亚州研究基金会 | 2022-06-10 | — | — | CN | disclosed |
| US-20220072153-A1 | REGENERATING FUNCTIONAL NEURONS FOR TREATMENT OF DISEASE AND INJURY IN THE NERVOUS SYSTEM | THE PENN STATE RESEARCH FOUNDATION (US) | 2022-03-10 | — | — | US | disclosed |
| US-20210369808-A1 | CHEMICAL REPROGRAMMING OF HUMAN GLIAL CELLS INTO NEURONS FOR BRAIN AND SPINAL CORD REPAIR | THE PENN STATE RESEARCH FOUNDATION | 2021-12-02 | — | — | US | disclosed |
| US-11167044-B2 | Regenerating functional neurons for treatment of disease in the nervous system | THE PENN STATE RESEARCH FOUNDATION (US) | 2021-11-09 | — | — | US | disclosed |
| CN-113559281-A | Regenerating functional neurons for treatment of disease and injury in the nervous system | 宾夕法尼亚州研究基金会 | 2021-10-29 | — | — | CN | disclosed |
| US-9266196-B2 | Ag ball, ag core ball, flux-coated ag ball, flux-coated ag core ball, solder joint, formed solder, solder paste and ag paste | SENJU METAL INDUSTRY CO., LTD. (JP) | 2016-02-23 | — | — | US | disclosed |
| US-20150250900-A1 | REGENERATING FUNCTIONAL NEURONS FOR TREATMENT OF DISEASE AND INJURY IN THE NERVOUS SYSTEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-09-10 | — | — | US | disclosed |
| EP-2905349-A2 | Ag ball, Ag core ball, flux-coated Ag ball, flux-coated Ag core ball, solder joint, formed solder, solder paste and Ag paste | SENJU METAL INDUSTRY CO., LTD. (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-20150217409-A1 | Ag BALL, Ag CORE BALL, FLUX-COATED Ag BALL, FLUX-COATED Ag CORE BALL, SOLDER JOINT, FORMED SOLDER, SOLDER PASTE AND Ag PASTE | Senju Metal lndustry Co., Ltd. (JP) | 2015-08-06 | — | — | US | disclosed |
| WO-2014015261-A1 | REGENERATING FUNCTIONAL NEURONS FOR TREATMENT OF DISEASE AND INJURY IN THE NERVOUS SYSTEM | THE PENN STATE RESEARCH FOUNDATION (US) | 2014-01-23 | — | — | WO | disclosed |
| US-20140024599-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF DISEASE OR INJURY OF THE NERVOUS SYSTEM | THE PENN STATE RESEARCH FOUNDATION (US) | 2014-01-23 | — | — | US | disclosed |
| WO-1999062978-A1 | POWDER-PAINT BINDER COMPOSITION | DSM N.V. (NL) | 1999-12-09 | — | — | WO | disclosed |
| US-4099975-A | Intumescent fire retardant compositions containing pentaerythritol cyclic diphosphates | VELSICOL CHEMICAL CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |
| US-3997505-A | Flame retardant polymeric compositions containing pentaerythritol cyclic diphosphates or diphosphoramidates | MICHIGAN CHEMICAL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3978167-A | FIRE RETARDANTS | MICHIGAN CHEMICAL CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |