Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787810 | 1.00 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL19400309 | 1.00 | KDM4E (0.67) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL16303445 | 0.98 | KDM4E (0.62) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL16864576 | 0.96 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13445262 | 0.96 | KDM4E (0.61) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13453768 | 0.91 | KDM4E (0.58) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL13524268 | 0.89 | KDM4E (0.57) | KDM4EMAPK1HIF1AADRA1APAOX | |
| SCHEMBL23735524 | 0.87 | CASP2 (0.57) | ADRA1ANAMPTCASP2FAAHMEN1 | |
| SCHEMBL23735520 | 0.87 | CASP2 (0.57) | ADRA1ANAMPTCASP2FAAHMEN1 | |
| SCHEMBL23735519 | 0.85 | CASP2 (0.55) | ADRA1ANAMPTCASP2FAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| EP-3041468-B1 | CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-06-13 | — | — | EP | disclosed |
| US-9695300-B2 | Methods and systems for making reinforced thermoplastic composites, and the products | JOHNS MANVILLE (US) | 2017-07-04 | — | — | US | disclosed |
| US-20150011707-A1 | METHODS AND SYSTEMS FOR MAKING REINFORCED THERMOPLASTIC COMPOSITES, AND THE PRODUCTS | JOHNS MANVILLE | 2015-01-08 | — | — | US | disclosed |
| US-20140256776-A1 | TREATMENT OF CANCER AND OTHER CONDITIONS USING A TRANSCRIPTION FACTOR MODULATOR | C&C BIOPHARMA, LLC | 2014-09-11 | — | — | US | disclosed |
| US-8222423-B2 | Bifunctional histone deacetylase inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20090312363-A1 | BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-12-17 | — | — | US | disclosed |
| US-6518242-B1 | Derivatives of glycopeptide antibacterial agents | THERAVANCE, INC. | 2003-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312363-A1 | BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC2 | KDM4E 209/4885MAPK1 2892/4885HIF1A 1194/4885 |
| US-20140256776-A1 | TREATMENT OF CANCER AND OTHER CONDITIONS USING A TRANSCRIPTION FACTOR MODULATOR | RELA, NCOA1, NCOA2 | KDM4E 315/4885MAPK1 3539/4885HIF1A 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.