SCHEMBL8373516

SCHEMBL8373516

O=c1c2ccccc2sn1-c1ccc(I)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 13/20 0.74
PHOSPHO1 Q8TCT1 13/20 0.74
PMM2 O15305 10/20 0.74
G6PD P11413 6/20 0.74
APOBEC3G Q9HC16 3/20 0.74
KDM4E B2RXH2 3/20 0.74
ALDH1A1 P00352 3/20 0.74
MAPT P10636 3/20 0.74
PKM P14618 3/20 0.74
HPGD P15428 3/20 0.74
ALOX12 P18054 3/20 0.74
CASP3 P42574 2/20 0.74
NPSR1 Q6W5P4 2/20 0.74
TDP1 Q9NUW8 2/20 0.74
HSP90AA1 P07900 1/20 0.74
RAB9A P51151 2/20 0.71
NPC1 O15118 1/20 0.71
TP53 P04637 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
KDM5B Q9UGL1 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1898397 0.85 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL30562926 0.85 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL30738364 0.84 MPI (0.96) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL21033372 0.83 MPI (0.74) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL29910151 0.83 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL2443755 0.83 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL1900552 0.83 MPI (0.74) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL1894451 0.83 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL2537846 0.83 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL8371734 0.83 MPI (0.74) MPIPHOSPHO1PMM2G6PDAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644243-B1 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL CO (JP) 1999-01-27 EP disclosed