Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 10/20 | 1.00 |
| ▸ | PMM2 | O15305 | 8/20 | 1.00 |
| ▸ | G6PD | P11413 | 6/20 | 1.00 |
| ▸ | PHOSPHO1 | Q8TCT1 | 9/20 | 0.74 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | CASP3 | P42574 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371846 | 0.86 | MPI (0.77) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL30562926 | 0.85 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL1898397 | 0.85 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL10876068 | 0.85 | MPI (0.72) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL30738364 | 0.84 | MPI (0.96) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL2539354 | 0.83 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL2443755 | 0.83 | MPI (1.00) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL8371770 | 0.83 | MIF (0.77) | MPIPMM2G6PDPHOSPHO1MIF | |
| SCHEMBL21033372 | 0.83 | MPI (0.74) | MPIPMM2G6PDPHOSPHO1APOBEC3G | |
| SCHEMBL1900552 | 0.83 | MPI (0.74) | MPIPMM2G6PDPHOSPHO1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051193-B1 | THE USE OF N-HALOGENOPHENYL-BENZISOTHIAZOLES | A. Nattermann & Cie. GmbH (DE) | 1986-02-26 | — | — | EP | claimed |
| US-4397858-A | ANTIARTHRITIC, ANTIINFLAMMATORY | A. NATTERMANN & CIE GMBH (DE) | 1983-08-09 | — | — | US | claimed |
| EP-0051193-A1 | The use of N-halogenophenyl-benzisothiazoles | A. Nattermann & Cie. GmbH (DE) | 1982-05-12 | — | — | EP | claimed |
| US-11801262-B2 | Antibiotic compositions | THIOREDOXIN SYSTEMS AB (SE) | 2023-10-31 | — | — | US | disclosed |
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |
| US-11013730-B1 | Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith | THIOREDOXIN SYSTEMS AB (SE) | 2021-05-25 | — | — | US | disclosed |
| US-20200281967-A1 | Antibiotic Compositions | THIOREDOXIN SYSTEMS AB (SE) | 2020-09-10 | — | — | US | disclosed |
| US-10766873-B2 | Zuclopenthixol hydrochloride derivatives and Ebselen derivatives as ErbB2 inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2020-09-08 | — | — | US | disclosed |
| US-10653717-B2 | Antibiotic compositions | THIOREDOXIN SYSTEMS AB (SE) | 2020-05-19 | — | — | US | disclosed |
| US-20190307726-A1 | PHARMACEUTICAL FORMULATIONS | MOLECULAR DEFENSES CORP (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190031639-A1 | ZUCLOPENTHIXOL HYDROCHLORIDE DERIVATIVES AND EBSELEN DERIVATIVES AS ERBB2 INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2019-01-31 | — | — | US | disclosed |
| US-5507862-A | PROTECTIVE COATINGS CONTAINING SUBSTITUTED N-PHENYLISOTHIAZOLONES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5508416-A | HALOGENATING A 2-(ALKYLTHIO)BENZAMIDE, CYCLIZATION TO HETERO RING AND N-S LINKAGE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0657438-A2 | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |
| EP-0051193-B1 | THE USE OF N-HALOGENOPHENYL-BENZISOTHIAZOLES | A. Nattermann & Cie. GmbH (DE) | 1986-02-26 | — | — | EP | disclosed |
| US-4397858-A | ANTIARTHRITIC, ANTIINFLAMMATORY | A. NATTERMANN & CIE GMBH (DE) | 1983-08-09 | — | — | US | disclosed |
| US-4396413-A | BACTERICIDES, FUNGICIDES, ALGICIDES | ROHM AND HAAS COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4241214-A | BACTERICIDE, FUNGICIDE AND ALGAECIDE | ROHM AND HAAS COMPANY (US) | 1980-12-23 | — | — | US | disclosed |
| US-4150026-A | BACTERICIDES, FUNGICIDES, ALGICIDES | ROHM AND HAAS COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4062946-A | 3-ISOTHIAZOLONES | ROHM AND HAAS COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031639-A1 | ZUCLOPENTHIXOL HYDROCHLORIDE DERIVATIVES AND EBSELEN DERIVATIVES AS ERBB2 INHIBITORS | ERBB2, ERBB3, EGFR | MPI 2549/4885PMM2 2475/4885G6PD 4073/4885 |
| US-20190307726-A1 | PHARMACEUTICAL FORMULATIONS | GSS, GSR, MGST3 | MPI 2231/4885PMM2 4390/4885G6PD 672/4885 |
| US-20200281967-A1 | Antibiotic Compositions | MRPL21, RPS5, MRPS35 | MPI 750/4885PMM2 2715/4885G6PD 3030/4885 |
| US-11013730-B1 | Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith | SELENOI, TST, SCLY | MPI 1930/4885PMM2 4644/4885G6PD 1736/4885 |
| US-10653717-B2 | Antibiotic compositions | MRPL21, RPS5, MRPS35 | MPI 750/4885PMM2 2715/4885G6PD 3030/4885 |
| US-10766873-B2 | Zuclopenthixol hydrochloride derivatives and Ebselen derivatives as ErbB2 inhibitors | ERBB2, ERBB3, EGFR | MPI 2549/4885PMM2 2475/4885G6PD 4073/4885 |
| US-11801262-B2 | Antibiotic compositions | MRPL21, RPS5, MRPS35 | MPI 750/4885PMM2 2715/4885G6PD 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.