SCHEMBL2443755

SCHEMBL2443755

Cc1ccc(-n2sc3ccccc3c2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 13/20 1.00
PHOSPHO1 Q8TCT1 12/20 1.00
PMM2 O15305 11/20 1.00
G6PD P11413 5/20 1.00
APOBEC3G Q9HC16 3/20 1.00
KDM4E B2RXH2 2/20 1.00
ALDH1A1 P00352 2/20 1.00
MAPT P10636 2/20 1.00
PKM P14618 2/20 1.00
HPGD P15428 2/20 1.00
ALOX12 P18054 2/20 1.00
CASP3 P42574 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
RAB9A P51151 2/20 1.00
NPC1 O15118 1/20 1.00
TP53 P04637 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
KDM5B Q9UGL1 1/20 1.00
HSP90AA1 P07900 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29910151 1.00 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL25763324 0.91 MPI (0.89) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL1898397 0.85 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL30562926 0.85 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL8371772 0.85 MPI (0.77) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL30738364 0.84 MPI (0.96) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL1897990 0.83 G6PD (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL1900552 0.83 MPI (0.74) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL21033372 0.83 MPI (0.74) MPIPHOSPHO1PMM2G6PDAPOBEC3G
SCHEMBL1894451 0.83 MPI (1.00) MPIPHOSPHO1PMM2G6PDAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059072-A Backup control device and control method 中国商用飞机有限责任公司 2026-05-19 CN claimed
EP-4161221-B1 RIGID-FLEX PRINTED CIRCUIT BOARD INCLUDING BUILT-IN DIAGNOSTIC HAMILTON SUNDSTRAND CORP (US) 2026-05-13 EP claimed
US-12406713-B2 Probabilistic computing devices based on stochastic switching in a ferroelectric field-effect transistor INTEL CORPORATION (US) 2025-09-02 US claimed
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 US claimed
CN-119792523-A Application of KDM5B inhibitor in preparation of medicine for treating EBV-related epithelial tumors 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 2025-04-11 CN claimed
EP-4492688-A1 FAIL OPEN DETECTION Hamilton Sundstrand Corporation (US) 2025-01-15 EP claimed
CN-119276763-A Test equipment and method for realizing BBF.247 based on Mini OLT 太仓市同维电子有限公司 2025-01-07 CN claimed
CN-113885394-B Airborne data comprehensive acquisition and recording system and method 中国人民解放军海军航空大学青岛校区 2025-01-03 CN claimed
CN-115675914-B PBIT circuit for testing on-state of multi-channel electric detonator 航宇救生装备有限公司 2024-12-24 CN claimed
CN-118643383-A Aircraft brake configuration identification method 西安航空制动科技有限公司 2024-09-13 CN claimed
CN-115675914-A PBIT circuit for testing connection state of multi-path electric detonator 航宇救生装备有限公司 2023-02-03 CN claimed
US-11464784-B2 Inhibition of aminocylase 3 (AA3) in the treatment of cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-10-11 US claimed
CN-110474757-B Signal transmission method and device, storage medium, and electronic device 中兴通讯股份有限公司 2022-08-12 CN claimed
US-20220186183-A1 NOVEL GLIA-LIKE CELLS DIFFERENATIATED FROM SOMATIC CELLS, PREPARATION METHOD THEREFOR, COCKTAIL COMPOSITION FOR PREPARING SAME, CELL THERAPEUTIC AGENT FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME, AND METHOD FOR PREVENTING AND TREATING NEUROLOGICAL DISORDERS BY ADMINISTERING SAME Cellapeutics Bio (KR) 2022-06-16 US claimed
EP-4011367-A1 COMPOUNDS FOR USE IN THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-06-15 EP claimed
CN-216210579-U Airborne data comprehensive acquisition and recording system 中国人民解放军海军航空大学青岛校区 2022-04-05 CN claimed
CN-113973362-A Reinforced learning non-zero and non-cooperative multi-agent secure communication power control method 天津大学 2022-01-25 CN claimed
US-20200206239-A1 INHIBITION OF AMINOCYLASE 3 (AA3) IN THE TREATMENT OF CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-07-02 US claimed
WO-2019055825-A1 INHIBITION OF AMINOACYLASE 3 (AA3) IN THE TREATMENT OF CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-03-21 WO claimed
US-20150272939-A1 Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase YALE UNIVERSITY (US) 2015-10-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220186183-A1 NOVEL GLIA-LIKE CELLS DIFFERENATIATED FROM SOMATIC CELLS, PREPARATION METHOD THEREFOR, COCKTAIL COMPOSITION FOR PREPARING SAME, CELL THERAPEUTIC AGENT FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME, AND METHOD FOR PREVENTING AND TREATING NEUROLOGICAL DISORDERS BY ADMINISTERING SAME GMFG, HGF, BDNF MPI 4637/4885PHOSPHO1 3836/4885PMM2 2141/4885
US-20200206239-A1 INHIBITION OF AMINOCYLASE 3 (AA3) IN THE TREATMENT OF CANCER PLAAT3, HCCS, LAP3 MPI 3826/4885PHOSPHO1 3805/4885PMM2 3512/4885
US-11464784-B2 Inhibition of aminocylase 3 (AA3) in the treatment of cancer PLAAT3, HCCS, LAP3 MPI 3826/4885PHOSPHO1 3805/4885PMM2 3512/4885
US-20150272939-A1 Identification of Small Molecule Inhibitors of Jumonji AT-Rich Interactive Domain 1A (JARID1A) and 1B (JARID1B) Histone Demethylase KDM1B, KDM1A, JMJD1C MPI 4251/4885PHOSPHO1 3282/4885PMM2 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.