Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371183 | 0.96 | GRIN2B (0.44) | ALDH1A1KDM4EGRIN2BSIGMAR1PRMT5 | |
| SCHEMBL8373213 | 0.93 | GRIN2B (0.45) | ALDH1A1KDM4EGRIN2BSIGMAR1PRMT5 | |
| SCHEMBL8370296 | 0.84 | HTR1A (0.47) | ALDH1A1KDM4EGRIN2BSIGMAR1PRMT5 | |
| SCHEMBL8372377 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EGRIN2BSIGMAR1PRMT5 | |
| SCHEMBL8370262 | 0.81 | HTR1A (0.46) | ALDH1A1KDM4EGRIN2BSIGMAR1DRD2 | |
| SCHEMBL8371318 | 0.78 | GRIN2B (0.40) | ALDH1A1KDM4EGRIN2BSIGMAR1DRD2 | |
| SCHEMBL8371192 | 0.77 | HTR1A (0.45) | ALDH1A1KDM4EGRIN2BSIGMAR1DRD2 | |
| SCHEMBL9093351 | 0.75 | HTR1B (0.57) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL8373208 | 0.75 | GRIN2B (0.41) | GRIN2BSIGMAR1PRMT5DRD2DRD3 | |
| SCHEMBL9094353 | 0.72 | HTR1A (0.44) | ALDH1A1KDM4EGRIN2BSIGMAR1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671397-B1 | Alkylaminoindane compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-02-03 | — | — | EP | disclosed |
| US-5569669-A | Alkylaminoindane compounds | ADIR ET COMPAGNIE (FR) | 1996-10-29 | — | — | US | disclosed |
| EP-0671397-A1 | Alkylaminoindanes compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-13 | — | — | EP | disclosed |