Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371192 | 0.96 | HTR1A (0.45) | HTR1AADRA2ASLC6A2SLC6A4GRIN2B | |
| SCHEMBL8370296 | 0.96 | HTR1A (0.47) | HTR1AADRA2ASLC6A2SLC6A4GRIN2B | |
| SCHEMBL9124088 | 0.88 | HTR1A (0.52) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL8371183 | 0.84 | GRIN2B (0.44) | HTR1AGRIN2BSIGMAR1DRD2ADRA1D | |
| SCHEMBL8373213 | 0.81 | GRIN2B (0.45) | HTR1ASLC6A4GRIN2BSIGMAR1DRD2 | |
| SCHEMBL8374235 | 0.81 | ALDH1A1 (0.41) | HTR1AGRIN2BSIGMAR1DRD2ADRA1D | |
| SCHEMBL8371318 | 0.81 | GRIN2B (0.40) | HTR1AGRIN2BSIGMAR1DRD2ADRA1D | |
| SCHEMBL9121635 | 0.79 | HTR1A (0.47) | HTR1AADRA2ASLC6A2SLC6A4DRD2 | |
| SCHEMBL8317904 | 0.78 | HTR1A (0.51) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL8373208 | 0.77 | GRIN2B (0.41) | GRIN2BSIGMAR1DRD2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671397-B1 | Alkylaminoindane compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-02-03 | — | — | EP | claimed |
| US-5569669-A | Alkylaminoindane compounds | ADIR ET COMPAGNIE (FR) | 1996-10-29 | — | — | US | claimed |
| EP-0671397-A1 | Alkylaminoindanes compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-13 | — | — | EP | claimed |
| EP-0671397-B1 | Alkylaminoindane compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-02-03 | — | — | EP | disclosed |
| US-5569669-A | Alkylaminoindane compounds | ADIR ET COMPAGNIE (FR) | 1996-10-29 | — | — | US | disclosed |
| EP-0671397-A1 | Alkylaminoindanes compounds, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-13 | — | — | EP | disclosed |