Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18754397 | 0.81 | HTT (0.58) | HTTALDH1A1RAB9AKDM4ECYP1A2 | |
| SCHEMBL11157649 | 0.78 | HTT (0.42) | HTTNOS3NOS2ALDH1A1RAB9A | |
| Bromide SCHEMBL10919771 | 0.76 | HTT (0.49) | HTTALDH1A1RAB9AKDM4ECYP1A2 | |
| SCHEMBL8377550 | 0.74 | KMT2A (0.55) | HTTALDH1A1RAB9AKDM4ECYP1A2 | |
| SCHEMBL8377547 | 0.74 | KMT2A (0.44) | HTTALDH1A1RAB9AKDM4ECYP1A2 | |
| SCHEMBL8373773 | 0.69 | ALDH1A1 (0.40) | HTTNOS3NOS2CDK4CDK2 | |
| SCHEMBL8378700 | 0.69 | CSNK1A1 (0.36) | HTTNOS3NOS2CDK4CDK2 | |
| SCHEMBL11877443 | 0.69 | MAPK1 (0.60) | ALDH1A1RAB9AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL2193253 | 0.67 | L3MBTL1 (0.44) | HTTRAB9ACYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL16506921 | 0.67 | HTT (0.43) | HTTALDH1A1RAB9AKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930062-A1 | Compositions containing imidazo-pyridine derivatives for dying keratinous fibres and process | L'OREAL (FR) | 1999-07-21 | — | — | EP | claimed |
| US-5980585-A | NONTOXIC; HAIR DYE | L'OREAL (FR) | 1999-11-09 | — | — | US | disclosed |
| EP-0930062-A1 | Compositions containing imidazo-pyridine derivatives for dying keratinous fibres and process | L'OREAL (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0841904-A1 | ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997002021-A1 | ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-01-23 | — | — | WO | disclosed |
| US-3936435-A | Cationic heterocyclic-azo-heterocyclic compounds from 5-aminoimidazo-(1,2-A)pyridines | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |