Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375866 | 0.87 | NCEH1 (0.33) | BCHEACHENCEH1 | |
| SCHEMBL8375118 | 0.86 | NCEH1 (0.33) | NCEH1 | |
| SCHEMBL8374737 | 0.83 | RAB9A (0.34) | BCHEACHENCEH1 | |
| SCHEMBL8374755 | 0.79 | NCEH1 (0.32) | ACHENCEH1 | |
| SCHEMBL8378152 | 0.78 | — | — | |
| SCHEMBL8375879 | 0.75 | ITGB1 (0.32) | BCHEACHE | |
| SCHEMBL8378405 | 0.74 | NCEH1 (0.34) | BCHEACHENCEH1 | |
| SCHEMBL8376582 | 0.73 | ACHE (0.36) | BCHEACHENCEH1 | |
| SCHEMBL8375131 | 0.70 | NCEH1 (0.32) | NCEH1 | |
| Maleic Acid SCHEMBL8375138 | 0.63 | ZDHHC20 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821239-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE CAUSED BY CHOLINERGIC DEFICIT | FROMMER LAWRENCE & HUAG LLP (US) | 1998-10-13 | — | — | US | claimed |
| US-5869480-A | ALLEVIATING MEMORY DYSFUNCTION CHARACTERIZED BY CHOLINERGIC DEFICIT | HOECHST MARION ROUSSEL INC. (US) | 1999-02-09 | — | — | US | disclosed |
| US-5866565-A | ALZHEIMER'S DISORDERS | HOECHST MARION ROUSSEL INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5821239-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE CAUSED BY CHOLINERGIC DEFICIT | FROMMER LAWRENCE & HUAG LLP (US) | 1998-10-13 | — | — | US | disclosed |