Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593283 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1GUSBMEN1 | |
| SCHEMBL14740735 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1GUSBGAA | |
| SCHEMBL1501079 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL250199 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL5683257 | 0.79 | MAPT (0.46) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL8666124 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL10718630 | 0.77 | ALDH1A1 (0.36) | ALDH1A1HSD17B10TDP1MEN1KMT2A | |
| SCHEMBL8411120 | 0.77 | S100A4 (0.38) | ALDH1A1HSD17B10TDP1APOBEC3GMAPT | |
| SCHEMBL11757103 | 0.77 | ALDH1A1 (0.35) | ALDH1A1HSD17B10TDP1TRPV4 | |
| SCHEMBL9711589 | 0.77 | L3MBTL1 (0.36) | ALDH1A1HSD17B10TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929114-A | ADMINISTERING ANTIVIRAL COMPOUND WHICH EXTRUDES ZINC FROM NUCLEOCAPSID PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS | WARNER-LAMBERT COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5734081-A | Arylthio compounds | WARNER-LAMBERT COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5668291-A | THIOSUBSTITUTED PYRIDINES, TREATMENT OF AIDS AND HIV | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0775110-A1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004242-A1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |